Products and Services
Products and Services
Research and Development
About R&D
The company has a research, analysis, and development team of more than 200 people with various academic levels including PhDs and Masters, and they have rich industry experience.
To ensure the efficiency and quality of R&D, the company has established an advisory team composed of academicians, professors, doctors, and experts to provide strategic advice for the company's research and development.
While conducting independent R&D, the company has also carried out close horizontal cooperation with well-known domestic and foreign institutes. Currently, it has cooperated with the Chinese Academy of Medical Sciences, Zhengzhou University, Zhejiang University, Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, Beijing University of Chemical Technology, and other units, fully leveraging the advantages of industry-academia-research interaction to improve R&D efficiency. This close cooperation not only effectively strengthens resource integration but also greatly accelerates the speed and intensity of the company's technological innovation, providing strong technical support for the company's development.
The company's R&D work focuses on serving production and the market, mainly focusing on process development.
According to GMP requirements, it is our specialty to rapidly transform R&D results into industrial production within the specified time to meet customer needs.
R&D Capability
Reaction temperature: -100°C to 400°C
Reaction pressure: from atmospheric pressure to 10MPa;
The main production technologies currently proficient in are:
Chiral technology
Grignard reaction
BuLi reaction
Catalytic reduction
Oxidation reaction
Halogenation reaction
Friedel Crafts reaction
Alkylation reaction
Esterification reaction
Hydrolysis reaction
Phosgene substitution reaction
Nitration reaction
Diazotization reaction
Cross-coupling reaction
Borane reaction
Enzyme Engineering
Our enzyme engineer team focus on data-and model-driven biocatalytic process development, using smart enzyme discovery pipeline to integrate bioinformatics, physical simulation and machine-learning. We are dedicated specialists in expression systems such as E.coli, P.pastoris, S. cerevisiae & Bacillus, with In-house collection holds >2000 enzymes covering all the essential classes for drug synthesis. Our fermentation capabilities from 1 L to 20 m3 (up to 20,000 L/week), and parallel fermentation development from shake-flask to batch production in weeks. Successfully application has been conducted, for example MNR-01, Ketoreductases/ADHs and so on.
Polypeptide
The high lights of our peptide team are excellent technical proficiency of peptide synthesis purification and modification (SPPS,LPPS, hybrid approaches combining solid and liquid phases, peptide building block synthesis technology, and etc.) , adeptness extends to employing diverse protection strategies (Fmoc, t-Boc, Cbz.) and comprehensive range of peptide modification technologies (Amino acid side-chain modification, Terminal modifications, Cyclization modifications, PEGylation modifications, Fluorescent labeling modifications, Biotinylation modifications, Glycosylation modifications, and Isotope labeling modifications, etc.)
We offer a full spectrum of peptide of industrialization services: peptide building block, peptide API development and manufacturing, peptide CDMO service and Cosmetic peptide R&D and production.
Email:
Company Address:
No.5, Donghai 4th Avenue, Zhejiang Chemical Materials Base Linhai Zone, Taizhou,Zhejiang,China
